Ischemic Stroke in Young due to Combined Protein C and S Deficiency
نویسندگان
چکیده
منابع مشابه
Ischemic stroke due to protein C deficiency.
Plasma protein C exerts anticoagulatory effects by inactivating factors V and VIII. Hereditary protein C deficiency is transmitted as an autosomal dominant disorder. Homozygous individuals usually develop purpura fulminans as newborns; heterozygous protein C-deficient individuals are at increased risk for venous thrombosis and pulmonary embolism. However, arterial thrombosis has been only rarel...
متن کاملHereditary protein S deficiency leads to ischemic stroke.
Hereditary protein S (PS) deficiency is an independent risk factor for venous thromboembolism. However, the correlation between PS and arterial thrombotic disease, such as cerebral thrombosis, is not clear. The present study focused on the molecular mechanisms underlying ischemic stroke caused by a PS gene mutation in one family. The activity of antithrombin, protein C and PS in the plasma of t...
متن کاملLateral sinus thrombosis and haemorrhagic ischemic stroke with protein S deficiency in a young.
Stroke or cerebro-vascular disease is one of the most important causes of high morbidity and mortality throughout the world. Stroke in young individuals poses a major problem as these individuals are the earning members of the family. Ischemic strokes are increasingly being attributed to causes other than athero-thrombotic disease. Protein S deficiency is a disorder with increased risk of venou...
متن کاملStroke in young with primary protein--S deficiency.
Stroke in young is a major health problem in developing countries along with CAD, according to various Indian studies its prevalence is 25-34%. Thrombophilic disorders constitute aetiology in 60% cases of stroke of undetermined aetiology. A 20 yrs old young female presented with symptoms of left PCA thrombosis (P2 syndrome), on evaluation--Isolated Protein--S deficiency is noticed. In this case...
متن کاملIschemic stroke due to deficiency of coagulation inhibitors. Report of 10 young adults.
BACKGROUND AND PURPOSE Deficiencies in coagulant inhibitors protein C, protein S, and antithrombin III increase the risk of venous thrombosis. We describe 10 young adults with cerebral arterial thrombosis due to deficiencies in these factors. METHODS Sixty patients younger than 45 years were hospitalized because of acute ischemic stroke diagnosed through computed tomography or magnetic resona...
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ژورنال
عنوان ژورنال: Journal of Case Reports
سال: 2013
ISSN: 2231-6809
DOI: 10.17659/01.2013.0005